Nelson Makamo was born in a small town of Nylstroom (now Modimolle), Limpopo province, in 1982. Makamo moved to Johannesburg to join the Artist Proof Studio in January 2003 where he studied for 3 years and worked for another 2 years as sales representative and curator of the gallery.
He was awarded a bursary from Johnson and Johnson and the Pinpoint one Human Resources Scholarship in 2005. Makamo has exhibited in group and solo exhibitions in South Africa, France, Italy, America, Netherlands, Amsterdam and Scotland.
His first solo exhibition, Walk with Me, was held at the Obert Contemporary Gallery in Melrose Arch, Johannesburg.